수다닷컴

병원나이 60세 이십니다.Gross FIndings
Part1 is a piece of adipose tissue containg lymph nodes, up to 0.8cm in diameter.
Entirely embedded(AFS and BFS).
Diagnosis : No tumor (0/3) (GHK)
Part 2 is a lump of breast(784*3.5cm) with attached skin (2*1).
On sections, there is an ill-defined, whitish nodule(0.8*0.5cm). It is located 2cm, 3.5cm, 2cm, 1.5cm
and 1cm from superior, inferior, medial, lateral and deep margins.
respectively. Representative sections.
CFS : tomor with clsest deep margin.
1F : Superior margni, 2F : inferior margin, 3F: medial margin, 4F: lateral margin, 5F: deep margin,
6-7F: tumor frozen diagnosis : clear deep margin(GHK)
(3Fro, 10HE, 1ER, 1PR, 1HER2, 1Ki-67, 1bcl-2, 1CK5/6, 1EGFR, 1AR)Microscopic finding
1.Nuclear pleomorphism : moderate
2.Mitotic counts : 5/10HPFs
Immunohistochemical stain
1.Estrogen receptor : Positive reaction
intensity : 3+
proportin : 90%
2.Progesterone receptor ; Positive reaction
intensity : 2+
proportion : 10%
3.HER-2/neu : Negative reaction(1)
4.Ki-67 labeling index : 5%
5.bcl-2 : Positive reaction (90%)
6.Epidermal growth factor receptor : Negative reaction
7.Cytokeratin 5/6 : Negative reaction
8.Androgen receptor : Positive reaction (40%)Diagnosis
Beast, left lower inner quadrant, breast conserving surgery and sentinel lymph node dissection
- Invasive lobular carcinoma (0.8cm) (pT1b)
- histologic grade 2
- nuclear grade 2
with 1)clear surgical resection margin
2) no lymphatic, angio, perineural invasion
3) no microcalcification
4) metastasis to 0 out of 3 lymph nodes (0/3) (pNo)

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